SPIP

Basic Package Attributes
AttributeValue
Title SPIP
Short Description SPIP simulates the transmission of genes from parents to offspring in a population having demographic structure defined by the user
Long Description SPIP simulates the transmission of genes from parents to offspring in a population having demographic structure defined by the user. Numerous variables controlling the age structure of the population, the number of offspring produced, the variance in male and female reproductive success, survival rates of different age classes, mate fidelity, duration of simulation, etc. can be specified by the user. The program stores the pedigree of all individuals in the simulated population. This pedigree is used to simulate genetic data on sampled individuals by tracing lineages back through paternal or maternal genes within each sampled individual. Data may be simulated for an arbitrary number of loci that are assumed to be independently segregating and to not be subject to natural selection, nor linked to any selected genes. Genotypes are reported in terms of both "founder alleles" (i.e., each distinct allele amongst the founders of the pedigree is given a distinct label) and also in terms of alleles whose frequencies amongst the founding members of the pedigree may be specified by the user.
Version 1.0
Project Started 2005
Last Release 13 years, 1 month ago
Homepagehttps://swfsc.noaa.gov/textblock.aspx?Division=FED&id=3434
Citations Salphati L, Childers K, Pan L, Tsutsui K, Takahashi L, Evaluation of a single-pass intestinal-perfusion method in rat for the prediction of absorption in man., J Pharm Pharmacol, July 1, 2001 [Abstract, cited in PMC ]
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