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GSR: Simulator - SimPEL
| Attribute | Value |
|---|---|
| Title | SimPEL |
| Short Description | SimPEL is short for Simulation-based Power Estimation for sequencing studies of Low-prevalence conditions. |
| Long Description | SimPEL is short for Simulation-based Power Estimation for sequencing studies of Low-prevalence conditions. SimPEL addresses the need for power estimation in low-prevalence condition studies, taking into account their inherently small sample sizes and analytical procedures. SimPEL integrates customizable parameters to realistically model study design outcomes and provide applicable information towards further refinement of experimental procedure. SimPEL is implemented as a function of the established JAWAMix5 tool (Long et al., 2013), an HDF5-based Java implementation for association mapping. |
| Keywords | genome-wide sequencing, power estimation, rare disease, adverse drug reactions,association analyses, genetic variant annotation |
| Version | 1.0 |
| Project Started | 2017 |
| Last Release | 5 years, 7 months ago |
| Homepage | https://github.com/precisionomics/SimPEL |
| Citations | Mak L, Li M, Cao C, Gordon P, Tarailo-Graovac M, Bousman C, Wang P, Long Q, SimPEL: Simulation-based power estimation for sequencing studies of low-prevalence conditions., Genet Epidemiol, 07-01-2018 [ Abstract, cited in PMC ] |
| GSR Certification | Accessibility |
| Last evaluated | 01-18-2023 (451 days ago) |
| Author verification | The basic description provided was derived from a website or publications by the GSR team and has not yet been verified by the simulation author. To modify this entry or add more information, propose changes to this simulator. |
| Attribute Category | Attribute |
|---|---|
| Target | |
| Type of Simulated Data | Genotype at Genetic Markers, Phenotype, |
| Variations | Single Nucleotide Variation, |
| Simulation Method | Resample Existing Data, |
| Input | |
| Data Type | Reference genome, |
| File format | |
| Output | |
| Data Type | |
| Sequencing Reads | |
| File Format | |
| Sample Type | |
| Phenotype | |
| Trait Type | |
| Determinants | |
| Evolutionary Features | |
| Demographic | |
| Population Size Changes | |
| Gene Flow | |
| Spatiality | |
| Life Cycle | |
| Mating System | |
| Fecundity | |
| Natural Selection | |
| Determinant | |
| Models | |
| Recombination | |
| Mutation Models | |
| Events Allowed | |
| Other | |
| Interface | Command-line, |
| Development | |
| Tested Platforms | Windows, Mac OS X, Linux and Unix, |
| Language | Java, |
| License | |
| GSR Certification | Documentation, |
Number of Primary Citations: 1
Number of Non-Primary Citations: 0
No example publication using SimPEL has been provided.
Please propose new citations if you are aware of publications that use this software.