SimPed

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Title SimPed
Short Description A Simulation Program to Generate Haplotype and Genotype Data for Pedigree Structures
Long Description SimPed is a program that quickly generates haplotype and/or genotype data for pedigrees of virtually any size and complexity. Marker data either in linkage disequilibrium or equilibrium can be generated for greater than 20,000 diallelic or multiallelic marker loci. Haplotypes and/or genotypes are generated for pedigree structures using specified genetic map distances and haplotype and/or allele frequencies. The simulated data generated by SimPed is useful for a variety of purposes, including evaluating methods that estimate haplotype frequencies for pedigree data, evaluating type I error due to intermarker linkage disequilibrium and estimating empirical p values for linkage and family-based association studies.
Project Started 2005
Last Release 9 years, 8 months ago
Homepagehttp://bioinformatics.org/simped/
Citations Leal SM, Yan K, Müller-Myhsok B, SimPed: a simulation program to generate haplotype and genotype data for pedigree structures., Hum Hered, Jan. 1, 2005 [Abstract, cited in PMC ]
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