GSR: Simulator - SIMLD
The SIMLD package is not yet public.
Attribute | Value |
---|---|
Title | SIMLD |
Short Description | Simulating Linkage Disequilibrium Structures in a Human Population for SNP Association Studies |
Long Description | Existing simulation methods usually simulate linkage disequilibrium (LD) structures starting with an initial population that is randomly generated according to specified allele frequencies. These at random based methods might be unstable because the LD level of the initial population is generally extremely low. This study presents a new algorithm, SIMLD, to simulate genome populations with real LD structures. SIMLD begins from an initial population with possibly the highest LD level, and then the LD decays to fit the desired level through processes of mating and recombination over generations. SIMLD can produce case–control samples according to various disease models. Using empirical SNP marker information from three populations of HapMap data, we implement the proposed algorithm and demonstrate a set of experimental results. |
Homepage | |
Citations | |
GSR Certification | This simulator has not yet been evaluated for GSR Certification. Learn more about or request GSR Certification. |
Author verification | The basic description provided was derived from a website or publications by the GSR team and has not yet been verified by the simulation author. To modify this entry or add more information, propose changes to this simulator. |
Attribute Category | Attribute |
---|---|
Target | |
Type of Simulated Data | |
Variations | |
Simulation Method | |
Input | |
Data Type | |
File format | |
Output | |
Data Type | |
Sequencing Reads | |
File Format | |
Sample Type | |
Phenotype | |
Trait Type | |
Determinants | |
Evolutionary Features | |
Demographic | |
Population Size Changes | |
Gene Flow | |
Spatiality | |
Life Cycle | |
Mating System | |
Fecundity | |
Natural Selection | |
Determinant | |
Models | |
Recombination | |
Mutation Models | |
Events Allowed | |
Other | |
Interface | |
Development | |
Tested Platforms | |
Language | |
License | |
GSR Certification |
Number of Primary Citations: 0
Number of Non-Primary Citations: 0
No example publication using SIMLD has been provided.
Please propose new citations if you are aware of publications that use this software.