SIMLA

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Basic Package Attributes
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Title SIMLA
Short Description SIMLA is a SIMuLAtion program that generates data sets of families for use in Linkage and Association studies.
Long Description SIMLA is a SIMuLAtion program that generates data sets of families for use in Linkage and Association studies. It allows the user flexibility in specifying marker and disease placement, locus heterogeneity, disequilibrium between markers and between markers and disease loci. Output is in the form of a LINKAGE (Lathrop et al., Proc Natl Acad Sci USA 81, 1984) pedigree file and is easily utilized, either directly or with minimal reformatting, as input for various genetic analysis packages.
Version 3.2
Project Started 2005
Last Release 14 years, 5 months ago
Homepagehttp://dmpi.duke.edu/simla-simulation-software-version-32
Citations Schmidt M, Hauser ER, Martin ER, Schmidt S, Extension of the SIMLA package for generating pedigrees with complex inheritance patterns: environmental covariates, gene-gene and gene-environment interaction., Stat Appl Genet Mol Biol, Jan. 1, 2005 [Abstract, cited in PMC ]
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