| Title || SimCopy |
| Short Description || An R package simulating the evolution of copy number profiles along a tree. |
| Long Description || SimCopy is an R package simulating the evolution of copy number profiles along a tree. It relies on the PhyloSim package for performing the simulations by encoding the genomic regions as sites in sequences and using modified processes acting on them. Please note, that the SimCopy simulations are restricted to a single chromosome. The genomes are encoded as a sequence of sites containing integers identifying genomic regions. Negative integers represent inverted genomic regions. SimCopy supports 1) deletion - deletes genomic regions, 2) duplication - duplicates genomic regions, 3) inversion - changes the orientation of the genomic regions by taking the opposite of the corresponding integer, 4) inverted duplication - duplicates genomic regions and flips their orientation and 5) translocation - translocates a stretch of genomic regions.
| Version || 0.2 |
| Project Started || 2012 |
| Last Release || 6 years, 3 months ago |
Roland F. Schwarz, Anne Trinh, Botond Sipos, James D. Brenton, Nick Goldman, and Florian Markowetz , Phylogenetic Quantification of Intra-tumour Heterogeneity, PLoS Comput Biol, April 10, 2014
|Author verification||The basic description provided was derived from a website or publications by the GSR team and has not yet been verified by the simulation author. To modify this entry or add more information, propose changes to this simulator.|