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GSR: Simulator - SIBSIM
| Attribute | Value |
|---|---|
| Title | SIBSIM |
| Short Description | Quantitative phenotype simulation in extended pedigrees |
| Long Description | SIBSIM is a modern and powerful computer program to simulate genotype and quantitative trait data in extended pedigrees. In the current release (2.1.2), we put emphasis on the simulation of a quantitative trait in pedigrees of arbitrary size without monozygotic twins. Well known software as, e.g., the SIMULATE package are not as scalable as SIBSIM. As an advantage over both G.A.S.P. and SIMLA no predefined boundaries restrict SIBSIM in its potential, neither in genome nor in family size. Instead, SIBSIM is as highly scalable as possible to meet any needs. SIBSIM may not only be used in simulation studies, but also in the validation, verification and testing process of other applications which deal with the implementation of statistical analysis of genomic data. We successfully used SIBSIM in the latter respect and detected a bug in a widely used genetic epidemiological software package. |
| Version | 2.1.2 |
| Project Started | 2004 |
| Last Release | 18 years, 2 months ago |
| Homepage | http://sourceforge.net/projects/sibsim/  |
| Citations |
Franke D, Kleensang A, Ziegler A, SIBSIM - quantitative phenotype simulation in extended pedigrees , GMS Med Inform Biom Epidemiol , Feb. 21, 2006
[ Abstract
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| GSR Certification | ✔ Accessibility |
| Last evaluated | Feb. 25, 2020 (1842 days ago) |
| Author verification | The basic description provided was derived from a website or publications by the GSR team and has not yet been verified by the simulation author. To modify this entry or add more information, propose changes to this simulator. |
| Attribute Category | Attribute |
|---|---|
| Target | |
| Type of Simulated Data | Genotype at Genetic Markers |
| Variations | Biallelic Marker, Missing Genotypes |
| Simulation Method | Other |
| Input | |
| Data Type | Allele Frequencies |
| File format | XML |
| Output | |
| Data Type | Genotype or Sequence |
| Sequencing Reads | |
| File Format | Linkage |
| Sample Type | Sibpairs, Trios and Nuclear Families, Extended or Complete Pedigrees |
| Phenotype | |
| Trait Type | Quantitative |
| Determinants | Single Genetic Marker (Single di-allelic quantitative trait marker) |
| Evolutionary Features | |
| Demographic | |
| Population Size Changes | Constant Size |
| Gene Flow | |
| Spatiality | |
| Life Cycle | |
| Mating System | |
| Fecundity | |
| Natural Selection | |
| Determinant | |
| Models | |
| Recombination | |
| Mutation Models | |
| Events Allowed | |
| Other | |
| Interface | Command-line |
| Development | |
| Tested Platforms | Linux and Unix |
| Language | C or C++ |
| License | GNU Public License |
| GSR Certification | Accessibility |
Number of Primary Citations: 1
Number of Non-Primary Citations: 1
The following 1 publications are selected examples of applications that used SIBSIM.
2011
König IR, Schumacher J, Hoffmann P, Kleensang A, Ludwig KU, Grimm T, Neuhoff N, Preis M, Roeske D, Warnke A, et al., Mapping for dyslexia and related cognitive trait loci provides strong evidence for further risk genes on chromosome 6p21., Am J Med Genet B Neuropsychiatr Genet, Jan. 1, 2011 [Abstract]