Basic Package Attributes
Title ProteinEvolver
Short Description Simulation of protein evolution along phylogenies under structure-based substitution models
Long Description ProteinEvolver generates samples of protein-coding genes and protein sequences evolved along phylogenies under structure-based substitution models. These models consider the protein structure to evaluate candidate mutations, which can be accepted (substitutions) or rejected depending on the energy of the protein structure of the mutated sequence. The simulation of molecular evolution occurs along phylogenetic histories, which can be either user-specified or simulated by the coalescent modified with recombination (including recombination hotspots), migration, demographics and longitudinal sampling.
Version 1.2.0.
Project Started 2013
Last Release 7 years, 8 months ago
Citations Arenas M, Dos Santos HG, Posada D, Bastolla U, Protein evolution along phylogenetic histories under structurally constrained substitution models., Bioinformatics, Dec. 1, 2013 [Abstract, cited in PMC ]
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