OncoSimulR

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Title OncoSimulR
Short Description BioConductor package for Forward Genetic Simulation of Cancer Progresion with Epistasis
Long Description An R/BioConductor package that provides functions for forward population genetic simulation in asexual populations, with special focus on cancer progression. Fitness can be an arbitrary function of genetic interactions between multiple genes, including epistasis, order restrictions in mutation accumulation, and order effects. Simulations use continuous-time models and can include driver and passenger genes. Also included are functions for simulating random DAGs of the type found in Oncogenetic Tress, Conjunctive Bayesian Networks, and other tumor progression models, and for plotting and sampling from single or multiple realizations of the simulations, including single-cell sampling.
Version 1.99
Project Started 2015
Last Release 3 years, 7 months ago
Homepagehttps://github.com/rdiaz02/OncoSimul
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