| Title || MetaSim |
| Short Description || A tool to generate collections of synthetic reads that reflect the diverse taxonomical composition of typical metagenome data sets |
| Long Description || The aim of MetaSim is to provide a tool for the simulation of reads based on given genome sequences refecting (adaptable) error models of current sequencing technologies. Additionally, the user is able to determine the abundance of the chosen taxa. Therefore, MetaSim integrates an induced tree view of the NCBI taxonomy that can be used to interactively select taxa and inner nodes of the taxonomy to congure their relative abundances.
Another feature of MetaSim allows the user to simulate an evolved population of a single genome sequence, using a population simulator. This feature is aimed at simulating the common real world situation that many dierent, but closely related strains of a lineage coexist in the same habitat.
The resulting data sets can be used to plan and design metagenome studies and for evaluation and improvement of metagenomic software tools and assembly algorithms. |
| Version || V0.9.5 |
| Project Started || 2008 |
| Last Release || 10 years, 1 month ago |
Richter DC, Ott F, Auch AF, Schmid R, Huson DH, MetaSim: a sequencing simulator for genomics and metagenomics., PLoS One, Oct. 8, 2008
[Abstract, cited in
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