GSR: Simulator - Mendel's Accountant
Attribute | Value |
---|---|
Title | Mendel's Accountant |
Short Description | Mendel's Accountant (MENDEL) is an advanced numerical simulation program for modeling genetic change over time and was developed collaboratively by Sanford, Baumgardner, Brewer, Gibson and ReMine |
Long Description | MENDEL is a genetic accounting program that allows realistic numerical simulation of the mutation/selection process over time. MENDEL is applicable to either haploid or diploid organisms, having either sexual or clonal reproduction. Each mutation that enters the simulated population is tracked from generation to generation to the end of the experiment - or until that mutation is lost either as a result of selection or random drift. Using a standard personal computer, the MENDEL program can be used to generate and track millions of mutations within a single population. MENDEL's input variables include such things as mutation rate, distribution specifications for mutation effects, extent of dominance, mating characteristics, selection method, average fertility, heritability, non-scaling noise, linkage block properties, chromosome number, genome size, population size, population sub-structure, and number of generations. The MENDEL program outputs, both in tabular and graphic form, provide several types of data including: deleterious and beneficial mutation counts per individual, mean individual fitness as a function of generation count, distribution of mutation effects, and allele frequencies. MENDEL provides biologists with a new tool for research and teaching, and allows for the modeling of complex biological scenarios that would have previously been impossible. |
Version | 2.0 |
Project Started | 2009 |
Last Release | 11 years, 11 months ago |
Homepage | http://mendelsaccount.sourceforge.net/ |
Citations | Sanford J, Baumgardner J, Brewer W, Gibson P, ReMine W, Mendel's Accountant: a biologically realistic forward-time population genetics program, Scalable Computing: Practice and Experience, 01-01-2007 [ Abstract ] |
GSR Certification | ✔ Accessibility |
Last evaluated | 02-06-2020 (1506 days ago) |
Attribute Category | Attribute |
---|---|
Target | |
Type of Simulated Data | Genotype at Genetic Markers, |
Variations | Biallelic Marker, |
Simulation Method | Forward-time, |
Input | |
Data Type | Allele Frequencies, |
File format | |
Output | |
Data Type | Genotype or Sequence, Phenotypic Trait, Mutation, Fitness (Selection threshold, linkage block fitness effects distribution), |
Sequencing Reads | Other (Mutation accumulation count, population size, allele frequencies and percent fixation, distribution of accumulating mutational effects), |
File Format | |
Sample Type | Random or Independent, |
Phenotype | |
Trait Type | |
Determinants | |
Evolutionary Features | |
Demographic | |
Population Size Changes | Constant Size, Exponential Growth or Decline, Bottleneck, Carrying Capacity, User Defined, |
Gene Flow | Stepping Stone Models, Island Models, Sex or Age-Specific Migration Rates, Admixed Population, |
Spatiality | |
Life Cycle | |
Mating System | Random Mating, Selfing, |
Fecundity | Constant Number, |
Natural Selection | |
Determinant | |
Models | Directional Selection, Multi-locus models, Epistasis, Random Fitness Effects (An exponential-type weibull distribution is used ), |
Recombination | Varying Recombination Rates, |
Mutation Models | Heterogeneity among Sites, |
Events Allowed | |
Other | |
Interface | Graphical User Interface, Web-based, |
Development | |
Tested Platforms | Windows, Mac OS X, Linux and Unix, |
Language | C or C++, |
License | GNU Public License, |
GSR Certification | Accessibility, Documentation, |
Number of Primary Citations: 1
Number of Non-Primary Citations: 0
No example publication using Mendel's Accountant has been provided.
Please propose new citations if you are aware of publications that use this software.