| Title || Mason |
| Short Description || A package for the simulation of nucleotide data. |
| Long Description || Mason is a package for the simulation of nucleotide data. Starting with a genome, you can simulate variants and optionally also methylation levels. From this, reads of different technologies can be simulated, optionally simulating bisulphite treatment. The variants can also be specified as a VCF file.
The result are FASTQ files with the reads and optionally a SAM file with the alignment to the reference sequence.
Substeps of the process are available as standalone tools, e.g. for the simulation of reads from preselected/-simulated fragments, computing of genomic sequences with variants. The time intensive part of read simulation has been parallelized. |
| Project Started || 2010 |
| Last Release || 7 years, 1 month ago |
Holtgrewe, M., Mason – A Read Simulator for Second Generation Sequencing Data, Technical Report FU Berlin, June 1, 2010