A simulation tool for generating haplotype data with pre-specified allele frequencies and LD coefficients Long Description (required)
Package for haplotype data simulation. Haplotypes are generated such that their allele frequencies and linkage disequilibrium coefficients match those estimated from an input data set http://cran.r-project.org/web/packages/hapsim/index.html
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Summary of Proposed Changes Current Citations/Applications
[Pubmed ID: 16188927 ],
Montana G ,
HapSim: a simulation tool for generating haplotype data with pre-specified allele frequencies and LD coefficients. ,
Bioinformatics ,
12-01-2005 ,
https://www.ncbi.nlm.nih.gov/pubmed/?term=16188927, Primary Citation
[Pubmed ID: 35412455 ],
Li X, Jiang L, Xue C, Li MJ, Li M ,
A conditional gene-based association framework integrating isoform-level eQTL data reveals new susceptibility genes for schizophrenia. ,
Elife ,
04-12-2022 ,
https://www.ncbi.nlm.nih.gov/pubmed/?term=35412455, , Application
[Pubmed ID: 35460606 ],
Jiang L, Miao L, Yi G, Li X, Xue C, Li MJ, Huang H, Li M ,
Powerful and robust inference of complex phenotypes' causal genes with dependent expression quantitative loci by a median-based Mendelian randomization. ,
Am J Hum Genet ,
05-05-2022 ,
https://www.ncbi.nlm.nih.gov/pubmed/?term=35460606, , Application