CoaSim

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Title CoaSim
Short Description CoaSim is a tool for simulating the coalescent process with recombination and geneconversion under various demographic models.
Long Description CoaSim is a tool for simulating the coalescent process with recombination and geneconversion under various demographic models. It effectively constructs the ancestral recombination graph for a given number of individuals and uses this to simulate samples of SNP, micro-satellite, and other haplotypes/genotypes. The generated sample can afterwards be separated in cases and controls, depending on states of selected individual markers. The tool can accordingly also be used to construct cases and control data sets for association studies. CoaSim is written in C++, Guile Scheme and Python, and is available as source code (under the GNU General Public License, GPL) and as binary versions as Linux RPM files. The source code has been successfully compiled on various Linux and UNIX systems, under OS X and under Windows with Cygwin. As I have only limited access to architectures other than Linux, it is not possible for me to make binary distributions for other platforms, but if anyone is willing to build the distributions I will be more than happy to put them on this site.
Version 4.2.2
Project Started 2005
Last Release 8 years, 3 months ago
Homepagehttps://github.com/mailund/CoaSim
Citations Mailund T, Schierup MH, Pedersen CN, Mechlenborg PJ, Madsen JN, Schauser L, CoaSim: a flexible environment for simulating genetic data under coalescent models., BMC Bioinformatics, Oct. 14, 2005 [Abstract, cited in PMC ]
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Last evaluatedFeb. 27, 2019 (229 days ago)
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